Quality of heroin and heroin-related deaths
from 1987 to 1995 in Vienna, Austria

by
Risser D, Uhl A, Stichenwirth M, Honigschnabl S, Hirz W,
Schneider B, Stellwag-Carion C, Klupp N, Vycudilik W, Bauer G
Institute of Forensic Medicine,
University of Vienna,
Austria. daniele.risser@univie.ac.at
Addiction 2000 Mar; 95(3): 375-82


ABSTRACT

AIMS: To investigate the quality of heroin seized in Vienna between 1987 and 1995 and to examine whether there was a relationship between the quality of heroin and the rate of drug-related deaths. DESIGN: Reports of heroin seizure analysis and post-mortem reports of heroin-related deaths in Vienna from 1987 to 1995 were analysed. RESULTS: There were 386 seizures of heroin comprising a total weight of 25 640.12 g heroin. All the seizures were in the base form. All seizures also contained a diluent, mainly lactose. Additionally, in 95 seizures caffeine, in four seizures paracetamol and in three seizures metaqualon were detected. Of a total of 764 drug-related deaths 506 cases were classified as heroin-related deaths. In 336 cases other central nervous system-depressant drugs and/or alcohol could be detected in the blood in addition to morphine (polydrug heroin-related deaths). There was evidence of a trend towards greater polydrug involvement during the study period. The age of victims of polydrug heroin-related deaths remained unchanged over time while the age of victims of pure heroin-related deaths decreased significantly. The morphine concentration in the medulla oblongata in heroin-related deaths decreased significantly. Finally, there was no statistically significant relationship between the rate of heroin-related deaths per year and the diacetylmorphine concentration of heroin seizures in that year. CONCLUSION: The results did not substantiate the widely held belief that increases in heroin-related deaths could be explained by an increase in the quality of heroin.
Pain
Opioids
Fentanyl
Tramadol
Tolerance
Heroin Inc
Poppy tea
Speedballs
Dutch heroin
Endomorphins
P-glycoprotein
NMDA anatagonists
Heroin and nitric oxide
The extended amygdala
Heroin, GABAA and the NAcc
Baclofen, dopamine and heroin
Methadone, morphine and heroin


Go To Good Drug Guide
Refs
HOME
HedWeb
cannabis-marijuana.com
BLTC Research
Paradise-Engineering
The Hedonistic Imperative
When Is It Best to Take Crack Cocaine?